Title : NF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell death.

Pub. Date : 2012 Jul 11

PMID : 22784363






2 Functional Relationships(s)
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1 Suppression of caspase cleavage by the pan caspase inhibitor, Z-VAD-fmk, suppressed induction of LC3-B and Atg12 and reduced autophagic cell death, indicating caspase activity was essential for autophagic cell death induced by helenalin. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone autophagy related 12 Homo sapiens
2 Suppression of caspase cleavage by the pan caspase inhibitor, Z-VAD-fmk, suppressed induction of LC3-B and Atg12 and reduced autophagic cell death, indicating caspase activity was essential for autophagic cell death induced by helenalin. helenalin autophagy related 12 Homo sapiens