Title : Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer.

Pub. Date : 2013 Sep

PMID : 23769318






1 Functional Relationships(s)
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1 Erlotinib treatment at clinically relevant concentrations induced autophagy (increased LC3II expression, Atg-5/Atg12 conjugation, formation of AVO and p62 degradation) in sensitive NSCLC cell lines, via p53 nuclear translocation, AMPK activation and mTOR suppression. Erlotinib Hydrochloride autophagy related 12 Homo sapiens