Janus kinase 2 ; Homo sapiens






2295 Article(s)
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1 7488109 TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules. Biochem Biophys Res Commun 1995 Nov 2 1
2 7500025 Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells. J Exp Med 1995 Dec 1 2
3 7514165 Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor. J Biol Chem 1994 May 20 3
4 7517048 Receptor domains involved in signal transduction of prolactin and growth hormone. Proc Soc Exp Biol Med 1994 Jul 1
5 7518712 Cytokine receptors and signal transduction. Baillieres Clin Haematol 1994 Mar 1
6 7521688 Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor. Blood 1994 Sep 15 1
7 7522448 G-CSF induces tyrosine phosphorylation of the JAK2 protein in the human myeloid G-CSF responsive and proliferative cells, but not in mature neutrophils. Biochem Biophys Res Commun 1994 Sep 15 1
8 7525556 Differential tyrosine phosphorylation of JAK1, JAK2, and STAT1 by growth hormone and interferon-gamma in IM-9 cells. J Biol Chem 1994 Nov 4 4
9 7525847 IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases. J Exp Med 1994 Dec 1 1
10 7527392 Convergence of signaling by interleukin-3, granulocyte-macrophage colony-stimulating factor, and mast cell growth factor on JAK2 tyrosine kinase. J Biol Chem 1994 Dec 16 1
11 7527668 Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor. Blood 1994 Dec 15 3
12 7528775 Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12. J Exp Med 1995 Jan 1 2
13 7535764 Intracellular tyrosine residues of the human growth hormone receptor are not required for the signaling of proliferation or Jak-STAT activation. J Biol Chem 1995 Mar 31 3
14 7535773 Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2. J Biol Chem 1995 Mar 31 4
15 7537382 A single phosphotyrosine residue of the prolactin receptor is responsible for activation of gene transcription. Proc Natl Acad Sci U S A 1995 Apr 25 1
16 7537736 Proline-rich sequence-mediated Jak2 association to the prolactin receptor is required but not sufficient for signal transduction. J Biol Chem 1995 May 5 2
17 7539888 Amino acids of the human growth hormone receptor that are required for proliferation and Jak-STAT signaling. Mol Endocrinol 1995 Mar 1
18 7543102 Signal transduction by a CD16/CD7/Jak2 fusion protein. J Biol Chem 1995 Aug 4 4
19 7543416 The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases. Exp Hematol 1995 Aug 2
20 7556623 Herbimycin A suppresses NF-kappa B activation and tyrosine phosphorylation of JAK2 and the subsequent induction of nitric oxide synthase in C6 glioma cells. FEBS Lett 1995 Sep 11 5
21 7567993 Identification of a viability domain in the granulocyte/macrophage colony-stimulating factor receptor beta-chain involving tyrosine-750. Proc Natl Acad Sci U S A 1995 Sep 12 1
22 7579336 Distinct regions of the granulocyte colony-stimulating factor receptor are required for tyrosine phosphorylation of the signaling molecules JAK2, Stat3, and p42, p44MAPK. Blood 1995 Nov 15 3
23 7588209 Dexamethasone-induced antagonism of growth hormone (GH) action by down-regulation of GH binding in 3T3-F442A fibroblasts. Endocrinology 1995 Nov 1
24 7591091 Attenuation of gamma interferon-induced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: selective inhibition of signaling through Janus kinases and Stat1. Infect Immun 1995 Nov 4
25 7592760 Activation of the STAT3/acute phase response factor transcription factor by interleukin-5. J Biol Chem 1995 Oct 27 1
26 7594607 Mechanism of inhibition of eosinophil activation by transforming growth factor-beta. Inhibition of Lyn, MAP, Jak2 kinases and STAT1 nuclear factor. J Immunol 1995 Nov 1 1
27 7602114 The activation of the Jak-STAT 1 signaling pathway by IL-5 in eosinophils. J Immunol 1995 Jul 1 1
28 7615558 The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors. J Biol Chem 1995 Jul 21 4
29 7638186 Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proc Natl Acad Sci U S A 1995 Aug 1 1
30 7657660 Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor. J Biol Chem 1995 Sep 1 1
31 7673169 Mapping of the cytoplasmic domain of the human growth hormone receptor required for the activation of Jak2 and Stat proteins. J Biol Chem 1995 Sep 8 2
32 7677406 [Growth hormone receptor. Structure and signal transduction]. Ann Endocrinol (Paris) 1995 1
33 7708714 Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription. Proc Natl Acad Sci U S A 1995 Mar 28 1
34 7777500 Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation. Proc Natl Acad Sci U S A 1995 Jun 6 1
35 7780132 Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase, JAK2. Blood 1995 Jun 15 1
36 7782332 Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1. J Biol Chem 1995 Jun 16 3
37 7795229 Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets. Blood 1995 Jul 1 5
38 7840614 Stimulation of receptor-associated kinase, tyrosine kinase, and MAP kinase is required for prolactin-mediated macromolecular biosynthesis and mitogenesis in Nb2 lymphoma. Arch Biochem Biophys 1995 Jan 10 1
39 7868067 The GH receptor and signal transduction. Horm Res 1994 1
40 7888666 Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and Stat1 alpha. Blood 1995 Mar 15 1
41 7901766 Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway. Nature 1993 Nov 11 1
42 7925997 Phosphorylation of JAK2 in thrombin-stimulated human platelets. FEBS Lett 1994 Oct 3 13
43 7935373 Erythropoietin and interleukin-2 activate distinct JAK kinase family members. Mol Cell Biol 1994 Oct 1
44 7956946 Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase. Endocrinology 1994 Nov 2
45 7957877 JAK3 Janus kinase is involved in interleukin 7 signal pathway. FEBS Lett 1994 Oct 24 1
46 7995951 IgG immune complexes inhibit IFN-gamma-induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor. J Immunol 1995 Jan 1 1
47 8007942 JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol Cell Biol 1994 Jul 2
48 8041708 Receptor to nucleus signaling by prolactin and interleukin 2 via activation of latent DNA-binding factors. Proc Natl Acad Sci U S A 1994 Jul 19 1
49 8041779 Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains. Proc Natl Acad Sci U S A 1994 Jul 19 2
50 8068943 Erythropoietin induces association of the JAK2 protein tyrosine kinase with the erythropoietin receptor in vivo. Blood 1994 Sep 1 2