Title : Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway.

Pub. Date : 1993 Nov 11

PMID : 7901766






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Unlike IFNs alpha and beta, IFN-gamma induces rapid tyrosine phosphorylation of JAK2 in wild-type cells, and JAK2 immunoprecipitates from these cells show tyrosine kinase activity. Tyrosine Janus kinase 2 Homo sapiens