Title : Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription.

Pub. Date : 1995 Mar 28

PMID : 7708714






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mutation of the four proline residues in the conserved box 1 region of the GHR, which is responsible for binding and activation of JAK2 kinase, completely abolished GH-induced gene transcription but did not affect the GH-induced rise in [Ca2+]i. Proline Janus kinase 2 Homo sapiens