SC 560






202 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 9789085 Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A 1998 Oct 27 4
2 10668485 COX-2 inhibitors. A new class of antiangiogenic agents. Ann N Y Acad Sci 1999 1
3 10692251 The roles of the cyclo-oxygenases types one and two in prostaglandin synthesis in human fetal membranes at term. Placenta 2000 Jan 1
4 10773026 Role of constitutive cyclooxygenase-2 in prostaglandin-dependent secretion in mouse colon in vitro. J Pharmacol Exp Ther 2000 May 1
5 10848506 Inhibition of cyclooxygenase-2 prevents inflammation-mediated preterm labor in the mouse. Am J Physiol Regul Integr Comp Physiol 2000 Jun 1
6 10982765 NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2. Gastroenterology 2000 Sep 2
7 11027502 Functional coupling of cyclooxygenase 1 and 2 to discrete prostanoid synthases in liver macrophages. Biochem Biophys Res Commun 2000 Sep 24 1
8 11235022 Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from the guinea-pig isolated perfused lung. Inflamm Res 2001 Jan 1
9 11447268 Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration. Proc Natl Acad Sci U S A 2001 Jul 17 2
10 11518732 Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. J Clin Invest 2001 Aug 1
11 11595414 Inhibition of both COX-1 and COX-2 is required for development of gastric damage in response to nonsteroidal antiinflammatory drugs. J Physiol Paris 2001 Jan-Dec 2
12 11606477 COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib. FASEB J 2001 Dec 1
13 11805196 Cyclooxygenase isozyme expression and intimal hyperplasia in a rat model of balloon angioplasty. J Pharmacol Exp Ther 2002 Feb 2
14 11861778 Up-regulation of cyclooxygenase-2 by inhibition of cyclooxygenase-1: a key to nonsteroidal anti-inflammatory drug-induced intestinal damage. J Pharmacol Exp Ther 2002 Mar 2
15 11902807 Involvement of peripheral cyclooxygenase-1 and cyclooxygenase-2 in inflammatory pain. J Pharm Pharmacol 2002 Mar 1
16 11936620 Selective inhibition of COX-2 is beneficial to mice infected intranasally with VSV. Prostaglandins Other Lipid Mediat 2002 Feb 2
17 11950805 Recovery of ischaemic injured porcine ileum: evidence for a contributory role of COX-1 and COX-2. Gut 2002 May 1
18 11959090 Effects of cyclooxygenase-1/cyclooxygenase-2 inhibition on leukocyte/endothelial cell interactions in the rat mesentery. Eur J Pharmacol 2002 Apr 5 1
19 11966529 Up-regulation of COX-2 by inhibition of COX-1 in the rat: a key to NSAID-induced gastric injury. Aliment Pharmacol Ther 2002 Apr 2
20 12144036 Involvement of COX and NOS induction in the sympatho-activation during sepsis. Auton Neurosci 2002 Jun 28 1
21 12183660 Distinct roles for cyclooxygenases 1 and 2 in interleukin-1-induced behavioral changes. J Pharmacol Exp Ther 2002 Sep 1
22 12234603 Diverse functional coupling of cyclooxygenase 1 and 2 with final prostanoid synthases in liver macrophages. Biochem Pharmacol 2002 Oct 15 2
23 12393942 Severe hypoxia inhibits prostaglandin I(2) biosynthesis and vasodilatory responses induced by ionophore A23187 in the isolated rabbit ear. Pharmacology 2002 Dec 1
24 12408376 Cyclooxygenase inhibitors block cell growth, increase ceramide and inhibit cell cycle. Breast Cancer Res Treat 2002 Nov 1
25 12411530 Endogenous cyclo-oxygenase activity regulates mouse gastric surface pH. J Physiol 2002 Nov 1 1
26 12438549 Role of cyclooxygenase (COX)-1 and COX-2 inhibition in nonsteroidal anti-inflammatory drug-induced intestinal damage in rats: relation to various pathogenic events. J Pharmacol Exp Ther 2002 Dec 2
27 12445211 The effects of cyclooxygenase isozyme inhibition on incisional wound healing in mouse skin. J Invest Dermatol 2002 Nov 1
28 12558194 Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation. Inflamm Res 2002 Dec 1
29 12608647 5-Hydroxytryptamine-induced plasma extravasation in the rat knee joint is mediated by multiple prostaglandins. Inflamm Res 2003 Jan 1
30 12637362 17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation. Am J Physiol Heart Circ Physiol 2003 Jul 1
31 12649264 Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cells. Circ Res 2003 Apr 18 2
32 12679329 Gender-dependent modulation of alpha 1-adrenergic responses in rat mesenteric arteries. Am J Physiol Heart Circ Physiol 2003 May 1
33 12763047 Mechanotransduction in bone cells proceeds via activation of COX-2, but not COX-1. Biochem Biophys Res Commun 2003 Jun 6 1
34 12832840 On the mechanisms underlying histamine induction of gastric mucosal lesions in rats with partial gastric vascular occlusion. J Pharmacol Sci 2003 Jun 1
35 12860547 The influence of a cyclooxygenase-1 inhibitor on injured and uninjured ligaments in the rat. Am J Sports Med 2003 Jul-Aug 1
36 12928598 Effects of selective cyclooxygenase inhibitors on ischemia/reperfusion-induced hepatic microcirculatory dysfunction in mice. Eur Surg Res 2003 Sep-Oct 2
37 12935431 Formulation dependent pharmacokinetics, bioavailability and renal toxicity of a selective cyclooxygenase-1 inhibitor SC-560 in the rat. J Pharm Pharm Sci 2003 May-Aug 2
38 12975491 Cyclooxygenase isozymes involved in adaptive functional responses in rat stomach after barrier disruption. J Pharmacol Exp Ther 2003 Nov 1
39 14569068 Interaction of cyclooxygenase isoenzymes, nitric oxide, and afferent neurons in gastric mucosal defense in rats. J Pharmacol Exp Ther 2004 Jan 1
40 14630622 NaCl transport across the opercular epithelium of Fundulus heteroclitus is inhibited by an endothelin to NO, superoxide, and prostanoid signaling axis. Am J Physiol Regul Integr Comp Physiol 2004 Mar 2
41 14630706 Genetic deficiency or pharmacological inhibition of cyclooxygenase-1 or -2 induces mouse keratinocyte differentiation in vitro and in vivo. FASEB J 2004 Jan 2
42 14633654 Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells. Carcinogenesis 2004 Mar 4
43 14690522 Modulation of beta-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures. J Neurochem 2004 Jan 1
44 14698037 COX-2-mediated PGD2 synthesis regulates phosphatidylcholine biosynthesis in rat renal papillary tissue. Biochem Pharmacol 2004 Jan 15 1
45 14752832 Role of thromboxane derived from COX-1 and -2 in hepatic microcirculatory dysfunction during endotoxemia in mice. Hepatology 2004 Jan 2
46 15059644 Cyclooxygenase 1-dependent production of F2-isoprostane and changes in redox status during warm renal ischemia-reperfusion. Free Radic Biol Med 2004 Apr 15 1
47 15075458 Role of COX inhibition in pathogenesis of NSAID-induced small intestinal damage. J Physiol Pharmacol 2003 Dec 3
48 15082878 Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach. J Physiol Pharmacol 2004 Mar 1
49 15090369 5-Oxo-ETE regulates tone of guinea pig airway smooth muscle via activation of Ca2+ pools and Rho-kinase pathway. Am J Physiol Lung Cell Mol Physiol 2004 Oct 2
50 15104355 Functional mechanism underlying COX-2 expression following administration of indomethacin in rat stomachs: importance of gastric hypermotility. Dig Dis Sci 2004 Feb 1