| 1 | 1384488 | Differential gene expression and regulation of type-1 angiotensin II receptor subtypes in the rat. | Biochem Biophys Res Commun | 1992 Oct 15 |
2 |
| 2 | 1435062 | Hypotensive activity of TCV-116, a newly developed angiotensin II receptor antagonist, in spontaneously hypertensive rats. | Life Sci | 1992 |
3 |
| 3 | 7500546 | Comparable effects of angiotensin II and converting enzyme blockade on hemodynamics and cardiac hypertrophy in spontaneously hypertensive rats. | Jpn Circ J | 1995 Sep |
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| 4 | 7533141 | Regulation of neuronal nitric oxide synthase in rat adrenal medulla. | Hypertension | 1995 Mar |
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| 5 | 7621917 | Effects of TCV-116 and CV-11974 on angiotensin II-induced responses in vascular smooth muscle cells. | Eur J Pharmacol | 1995 Apr 28 |
3 |
| 6 | 7714806 | Angiotensin II type I receptor antagonist inhibits the gene expression of transforming growth factor-beta 1 and extracellular matrix in cardiac and vascular tissues of hypertensive rats. | J Pharmacol Exp Ther | 1995 Apr |
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| 7 | 7768570 | Angiotensin II induces cardiac phenotypic modulation and remodeling in vivo in rats. | Hypertension | 1995 Jun |
1 |
| 8 | 7788922 | Angiotensin II type 1 receptor blockade inhibits the expression of immediate-early genes and fibronectin in rat injured artery. | Circulation | 1995 Jul 1 |
6 |
| 9 | 7810730 | Chronic administration of angiotensin II receptor antagonist, TCV-116, in cardiomyopathic hamsters. | Am J Physiol | 1994 Dec |
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| 10 | 7843746 | Characterization of the angiotensin II receptor antagonist TCV-116 in healthy volunteers. | Hypertension | 1995 Jan |
9 |
| 11 | 7853793 | Contribution of renal angiotensin II type I receptor to gene expressions in hypertension-induced renal injury. | Kidney Int | 1994 Nov |
6 |
| 12 | 7858853 | AT1 receptor-mediated stimulation by angiotensin II of rat aortic fibronectin gene expression in vivo. | Br J Pharmacol | 1994 Nov |
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| 13 | 7867037 | Transforming growth factor beta 1 and extracellular matrix gene expression in isoprenaline induced cardiac hypertrophy: effects of inhibition of the renin-angiotensin system. | Cardiovasc Res | 1994 Dec |
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| 14 | 7884578 | TCV 116 prevents progressive renal injury in rats with extensive renal mass ablation. | J Hypertens Suppl | 1994 Nov |
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| 15 | 7884581 | Angiotensin II antagonists DuP 753 and TCV 116. | J Hypertens Suppl | 1994 Nov |
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| 16 | 7884582 | Angiotensin II receptor antagonists versus angiotensin converting enzyme inhibitors: effects on renal function. | J Hypertens Suppl | 1994 Nov |
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| 17 | 7889191 | Gene expression of the type-1 angiotensin II receptor in rat adrenal gland. | Blood Press Suppl | 1994 |
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| 18 | 7889192 | Effects of an angiotensin II receptor antagonist, TCV-116, on insulin sensitivity in fructose-fed rats. | Blood Press Suppl | 1994 |
2 |
| 19 | 7889195 | Role of the renin-angiotensin system in hypertension in the elderly. | Blood Press Suppl | 1994 |
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| 20 | 7889200 | Effect of an angiotensin II receptor antagonist, TCV-116, on rat carotid artery neointimal formation after balloon injury. | Blood Press Suppl | 1994 |
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| 21 | 7889201 | Renal protective effect of TCV-116 in stroke-prone spontaneously hypertensive rats. | Blood Press Suppl | 1994 |
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| 22 | 7889207 | Enhancement of hypertension and renal injury by salt-loading during chronic nitric oxide inhibition. Effects of TCV-116, a novel angiotensin II receptor antagonist. | Blood Press Suppl | 1994 |
4 |
| 23 | 7889210 | Angiotensin II receptor antagonist, TCV-116, prevents myocardial hypertrophy in spontaneously hypertensive rats. | Blood Press Suppl | 1994 |
5 |
| 24 | 7889211 | Effect of an angiotensin II receptor antagonist, TCV-116, on cardiac hypertrophy and coronary circulation in spontaneously hypertensive rats. | Blood Press Suppl | 1994 |
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| 25 | 8013547 | Effect of an angiotensin II receptor antagonist, CV-11974, and its prodrug, TCV-116, on production of aldosterone. | Eur J Pharmacol | 1994 Feb 21 |
1 |
| 26 | 8039844 | Role of angiotensin II in renal injury of deoxycorticosterone acetate-salt hypertensive rats. | Hypertension | 1994 Aug |
1 |
| 27 | 8065233 | Effect of angiotensin II type 1 receptor antagonist on urinary prostaglandin E2 excretion following furosemide in rats. | Life Sci | 1994 |
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| 28 | 8138966 | Antihypertensive effects of a highly potent and long-acting angiotensin II subtype-1 receptor antagonist, (+-)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H- benzimidazole-7-carboxylate (TCV-116), in various hypertensive rats. | J Pharmacol Exp Ther | 1994 Mar |
2 |
| 29 | 8181146 | Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro. | Circulation | 1994 May |
4 |
| 30 | 8201847 | TCV-116, a newly developed angiotensin II receptor antagonist, induces regression of cardiac hypertrophy through suppression of the tissue renin-angiotensin system in spontaneously hypertensive rats. | Life Sci | 1994 |
7 |
| 31 | 8205603 | Effects of the angiotensin II receptor antagonist, TCV-116, on blood pressure and the renin-angiotensin system in healthy subjects. | Clin Ther | 1994 Jan-Feb |
2 |
| 32 | 8221818 | Pilot study of a new angiotensin II receptor antagonist, TCV-116: effects of a single oral dose on blood pressure in patients with essential hypertension. | Clin Ther | 1993 Jul-Aug |
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| 33 | 8301670 | Contribution of cardiac renin-angiotensin system to ventricular remodelling in myocardial-infarcted rats. | J Mol Cell Cardiol | 1993 Nov |
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| 34 | 8505091 | Role of angiotensin II in high fructose-induced left ventricular hypertrophy in rats. | Hypertension | 1993 Jun |
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| 35 | 8523451 | Inhibition by angiotensin II type 1 receptor antagonist of cardiac phenotypic modulation after myocardial infarction. | J Mol Cell Cardiol | 1995 Sep |
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| 36 | 8548907 | Angiotensin II receptor antagonist TCV-116 reduces graft coronary artery disease and preserves graft status in a murine model. A comparative study with captopril. | Circulation | 1996 Jan 15 |
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| 37 | 8583480 | Effect of angiotensin II blockade on cardiac hypertrophy and remodelling: a review. | J Hum Hypertens | 1995 Nov |
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| 38 | 8583793 | Persistent inhibition of the pressor and aldosterone responses to angiotensin-II by TCV-116 in normotensive subjects. | J Cardiovasc Pharmacol | 1995 Sep |
11 |
| 39 | 8603580 | Angiotensin II-dependent down-regulation of vascular natriuretic peptide type C receptor gene expression in hypertensive rats. | Endocrinology | 1996 Mar |
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| 40 | 8674841 | Effect of dietary chloride on aldosterone synthase induction and angiotensin II receptors in rat adrenals. | Mol Cell Endocrinol | 1995 Oct 30 |
2 |
| 41 | 8678895 | CV-11974, the active metabolite of TCV-116 (Candesarten), inhibits the synergistic or additive effect of different growth factors on angiotensin II-induced proliferation of vascular smooth muscle cells. | Biochem Pharmacol | 1996 Jul 12 |
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| 42 | 8682082 | Immunomodulating agents for the management of heart failure with myocarditis and cardiomyopathy--lessons from animal experiments. | Eur Heart J | 1995 Dec |
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| 43 | 8717062 | AT1 receptor antagonist, TCV 116, does not prevent cardiac hypertrophy in salt-loaded Dahl salt-sensitive rats. | Clin Exp Pharmacol Physiol | 1996 Apr |
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| 44 | 8738803 | Angiotensin II and calcium blockers prevent glomerular phenotypic changes in remnant kidney model. | J Am Soc Nephrol | 1996 May |
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| 45 | 8743529 | TCV-116 inhibits renal interstitial and glomerular injury in glomerulosclerotic rats. | Kidney Int Suppl | 1996 Jun |
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| 46 | 8986455 | Combined effects of the angiotensin II antagonist candesartan cilexetil (TCV-116) and other classes of antihypertensive drugs in spontaneously hypertensive rats. | Hypertens Res | 1996 Dec |
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| 47 | 9039142 | Improvement in baroreflex function by an oral angiotensin receptor antagonist in rats with myocardial infarction. | Hypertension | 1997 Jan |
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| 48 | 9072428 | Effect of an angiotensin II receptor antagonist, TCV-116, on neointimal formation following balloon injury in the SHR carotid artery. | Clin Exp Pharmacol Physiol Suppl | 1995 Dec |
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| 49 | 9110382 | Modulation of renal glomerular angiotensin II receptors by ace inhibition and AT1 receptor antagonism. | Regul Pept | 1997 Jan 29 |
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| 50 | 9321751 | Pressure overload per se rather than cardiac angiotensin converting enzyme activity may be important in the development of rat cardiac hypertrophy. | J Hypertens | 1997 Sep |
2 |