Title : AT1 receptor-mediated stimulation by angiotensin II of rat aortic fibronectin gene expression in vivo.

Pub. Date : 1994 Nov

PMID : 7858853






3 Functional Relationships(s)
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1 Treatment with TCV-116 (3 mg kg-1 day-1), a non-peptide selective AT1 receptor antagonist, completely inhibited the angiotensin II-induced increase in aortic fibronectin mRNA, while hydralazine (10 mg kg-1 day-1) did not block this effect. candesartan cilexetil angiotensin II receptor, type 1a Rattus norvegicus
2 Treatment with TCV-116 (3 mg kg-1 day-1), a non-peptide selective AT1 receptor antagonist, completely inhibited the angiotensin II-induced increase in aortic fibronectin mRNA, while hydralazine (10 mg kg-1 day-1) did not block this effect. candesartan cilexetil angiotensinogen Rattus norvegicus
3 Treatment with TCV-116 (3 mg kg-1 day-1), a non-peptide selective AT1 receptor antagonist, completely inhibited the angiotensin II-induced increase in aortic fibronectin mRNA, while hydralazine (10 mg kg-1 day-1) did not block this effect. candesartan cilexetil fibronectin 1 Rattus norvegicus