Title : Angiotensin II-dependent down-regulation of vascular natriuretic peptide type C receptor gene expression in hypertensive rats.

Pub. Date : 1996 Mar

PMID : 8603580






1 Functional Relationships(s)
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1 Oral administration of an angiotensin (Ang) II receptor (AT1) antagonist, TCV-116, but not a calcium channel blocker, manidipine, reversed the down-regulated NP-C receptor mRNA in SHR-SP/Izm to the level in WKY/Izm, whereas the latter was more potent in decreasing the blood pressure. candesartan cilexetil angiotensin II receptor, type 1a Rattus norvegicus