Pub. Date : 2021 Jul
PMID : 33831806
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hinokitiol inhibits RANKL-induced osteoclastogenesis in vitro and prevents ovariectomy-induced bone loss in vivo. | beta-thujaplicin | TNF superfamily member 11 | Homo sapiens |
| 2 | In this study, hinokitiol, a tropolone-related compound extracted from the heart wood of several cupressaceous plants, was found to inhibit RANKL-induced osteoclast formation and bone resorption in vitro. | beta-thujaplicin | TNF superfamily member 11 | Homo sapiens |
| 3 | Hinokitiol inhibited early activation of the ERK, p38, and JNK-MAPK pathways, thereby suppressing the activity and expression of downstream factors (c-Jun, c-Fos, and NFATC1). | beta-thujaplicin | mitogen-activated protein kinase 1 | Homo sapiens |
| 4 | Hinokitiol inhibited early activation of the ERK, p38, and JNK-MAPK pathways, thereby suppressing the activity and expression of downstream factors (c-Jun, c-Fos, and NFATC1). | beta-thujaplicin | mitogen-activated protein kinase 14 | Homo sapiens |
| 5 | Hinokitiol inhibited early activation of the ERK, p38, and JNK-MAPK pathways, thereby suppressing the activity and expression of downstream factors (c-Jun, c-Fos, and NFATC1). | beta-thujaplicin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 6 | Hinokitiol inhibited early activation of the ERK, p38, and JNK-MAPK pathways, thereby suppressing the activity and expression of downstream factors (c-Jun, c-Fos, and NFATC1). | beta-thujaplicin | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 7 | Hinokitiol inhibited early activation of the ERK, p38, and JNK-MAPK pathways, thereby suppressing the activity and expression of downstream factors (c-Jun, c-Fos, and NFATC1). | beta-thujaplicin | nuclear factor of activated T cells 1 | Homo sapiens |