Pub. Date : 2020 Aug 4
PMID : 32750045
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | THS-induced over-production of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in BALF and serum was suppressed by MaR1. | THYMIDINE-5'-(DITHIO)PHOSPHATE | interleukin 6 | Rattus norvegicus |
| 2 | THS-induced over-production of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in BALF and serum was suppressed by MaR1. | THYMIDINE-5'-(DITHIO)PHOSPHATE | interleukin 6 | Rattus norvegicus |
| 3 | THS-induced over-production of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in BALF and serum was suppressed by MaR1. | THYMIDINE-5'-(DITHIO)PHOSPHATE | tumor necrosis factor | Rattus norvegicus |
| 4 | THS-induced over-production of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in BALF and serum was suppressed by MaR1. | THYMIDINE-5'-(DITHIO)PHOSPHATE | tumor necrosis factor | Rattus norvegicus |
| 5 | Besides, the TLR4/p38MAPK/NF-kappaB pathway activation in THS-induced rats were inhibited by MaR1 treatment. | THYMIDINE-5'-(DITHIO)PHOSPHATE | toll-like receptor 4 | Rattus norvegicus |
| 6 | CONCLUSIONS Our study showed that MaR1 could effectively alleviated THS-induced lung injury via inhibiting the excitation of the TLR4/p38MAPK/NF-kappaB pathway in THS-induced rats, suggesting that MaR1 might be a novel agent for lung damage treatment. | THYMIDINE-5'-(DITHIO)PHOSPHATE | toll-like receptor 4 | Rattus norvegicus |
| 7 | CONCLUSIONS Our study showed that MaR1 could effectively alleviated THS-induced lung injury via inhibiting the excitation of the TLR4/p38MAPK/NF-kappaB pathway in THS-induced rats, suggesting that MaR1 might be a novel agent for lung damage treatment. | THYMIDINE-5'-(DITHIO)PHOSPHATE | toll-like receptor 4 | Rattus norvegicus |