Title : Extracellular ADP augments microglial inflammasome and NF-κB activation via the P2Y12 receptor.

Pub. Date : 2020 Feb

PMID : 31549730






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Both IL-1beta and IL-6 responses were augmented by extracellular ADP or ADP-betaS and were abrogated by PSB0739. adenosine 5'-O-(2-thiodiphosphate) interleukin 1 alpha Homo sapiens
2 Both IL-1beta and IL-6 responses were augmented by extracellular ADP or ADP-betaS and were abrogated by PSB0739. adenosine 5'-O-(2-thiodiphosphate) interleukin 6 Homo sapiens
3 Mechanistically, ADP-betaS potentiated NF-kappaB activation. adenosine 5'-O-(2-thiodiphosphate) nuclear factor kappa B subunit 1 Homo sapiens