Title : P2Y12 and P2Y13 receptors involved in ADPβs induced the release of IL-1β, IL-6 and TNF-α from cultured dorsal horn microglia.

Pub. Date : 2017

PMID : 28794655






6 Functional Relationships(s)
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1 ADPbetas-evoked increase in Iba-1, IL-1beta, IL-6 and TNF-alpha mRNA expression was inhibited only partially by P2Y12 receptor antagonist MRS2395 or P2Y13 receptor antagonist MRS2211, respectively. adenosine 5'-O-(2-thiodiphosphate) allograft inflammatory factor 1 Homo sapiens
2 ADPbetas-evoked increase in Iba-1, IL-1beta, IL-6 and TNF-alpha mRNA expression was inhibited only partially by P2Y12 receptor antagonist MRS2395 or P2Y13 receptor antagonist MRS2211, respectively. adenosine 5'-O-(2-thiodiphosphate) interleukin 1 beta Homo sapiens
3 ADPbetas-evoked increase in Iba-1, IL-1beta, IL-6 and TNF-alpha mRNA expression was inhibited only partially by P2Y12 receptor antagonist MRS2395 or P2Y13 receptor antagonist MRS2211, respectively. adenosine 5'-O-(2-thiodiphosphate) interleukin 6 Homo sapiens
4 ADPbetas-evoked increase in Iba-1, IL-1beta, IL-6 and TNF-alpha mRNA expression was inhibited only partially by P2Y12 receptor antagonist MRS2395 or P2Y13 receptor antagonist MRS2211, respectively. adenosine 5'-O-(2-thiodiphosphate) tumor necrosis factor Homo sapiens
5 ADPbetas-evoked increase in Iba-1, IL-1beta, IL-6 and TNF-alpha mRNA expression was inhibited only partially by P2Y12 receptor antagonist MRS2395 or P2Y13 receptor antagonist MRS2211, respectively. adenosine 5'-O-(2-thiodiphosphate) purinergic receptor P2Y12 Homo sapiens
6 ADPbetas-evoked increase in Iba-1, IL-1beta, IL-6 and TNF-alpha mRNA expression was inhibited only partially by P2Y12 receptor antagonist MRS2395 or P2Y13 receptor antagonist MRS2211, respectively. adenosine 5'-O-(2-thiodiphosphate) purinergic receptor P2Y13 Homo sapiens