Protein Name | allograft inflammatory factor 1 |
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Organism | Homo sapiens |
Gene ID | 199 |
Gene Symbol | AIF1 |
UniProt | P55008 (AIF1_HUMAN), I3WTX1 (I3WTX1_HUMAN), Q4V347 (Q4V347_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
126
Total Number of Articles : 142 |
Description |
allograft inflammatory factor 1 |
Gene Summary |
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016] |
synonyms |
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Properties | |