Protein Name allograft inflammatory factor 1
Organism Homo sapiens
Gene ID 199
Gene Symbol

AIF1

UniProt P55008 (AIF1_HUMAN), I3WTX1 (I3WTX1_HUMAN), Q4V347 (Q4V347_HUMAN)
Relationships Total Number of functionally related compound(s) : 126
Total Number of Articles : 142
Description

allograft inflammatory factor 1

Gene Summary

This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]

synonyms
  • allograft inflammatory factor 1
  • interferon gamma responsive transcript
  • ionized calcium-binding adapter molecule 1
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Properties