Title : Promoting endothelial function by S-nitrosoglutathione through the HIF-1α/VEGF pathway stimulates neurorepair and functional recovery following experimental stroke in rats.

Pub. Date : 2015

PMID : 25945035






4 Functional Relationships(s)
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1 GSNO treatment of IR not only remarkably enhanced further the expression of HIF-1alpha, VEGF, and PECAM-1 but also improved functioning compared with IR. S-Nitrosoglutathione platelet and endothelial cell adhesion molecule 1 Rattus norvegicus
2 2-ME treatment of the GSNO group also blocked not only GSNO"s effect of reduced infarct volume, decreased neuronal loss, and enhanced expression of PECAM-1 (P<0.001), but also its improvement of motor and neurological functions (P<0.001). 2-Methoxyestradiol platelet and endothelial cell adhesion molecule 1 Rattus norvegicus
3 2-ME treatment of the GSNO group also blocked not only GSNO"s effect of reduced infarct volume, decreased neuronal loss, and enhanced expression of PECAM-1 (P<0.001), but also its improvement of motor and neurological functions (P<0.001). S-Nitrosoglutathione platelet and endothelial cell adhesion molecule 1 Rattus norvegicus
4 2-ME treatment of the GSNO group also blocked not only GSNO"s effect of reduced infarct volume, decreased neuronal loss, and enhanced expression of PECAM-1 (P<0.001), but also its improvement of motor and neurological functions (P<0.001). S-Nitrosoglutathione platelet and endothelial cell adhesion molecule 1 Rattus norvegicus