| Protein Name | platelet and endothelial cell adhesion molecule 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 29583 |
| Gene Symbol | Pecam1 |
| UniProt | Q3SWT0 (PECA1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
155
Total Number of Articles : 167 |
Description |
platelet and endothelial cell adhesion molecule 1 |
| Gene Summary |
Enables protein phosphatase binding activity. Involved in several processes, including cellular response to type II interferon; negative regulation of GTPase activity; and negative regulation of actin filament polymerization. Located in cell surface and ruffle. Used to study pulmonary hypertension. Biomarker of bacterial pneumonia; orchitis; and osteoarthritis. Human ortholog(s) of this gene implicated in coronary artery disease; coronary stenosis; myocardial infarction; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |