Title : Ubiquitination by SAG regulates macrophage survival/death and immune response during infection.

Pub. Date : 2014 Sep

PMID : 24786833






1 Functional Relationships(s)
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1 SAG knockdown caused the accumulation of proapoptotic Bax and SARM, imbalance of Bcl-2/Bax in the mitochondria, induction of cytosolic cytochrome c and activation of caspase-9 and -3, all of which led to disequilibrium between life and death of macrophages. sagopilone sterile alpha and TIR motif containing 1 Homo sapiens