PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24786833-7	2014	SAG knockdown caused the accumulation of proapoptotic Bax and SARM, imbalance of Bcl-2/Bax in the mitochondria, induction of cytosolic cytochrome c and activation of caspase-9 and -3, all of which led to disequilibrium between life and death of macrophages.	sagopilone	0-3	BCL2 associated X, apoptosis regulator	Homo sapiens	54-57	
24786833-7	2014	SAG knockdown caused the accumulation of proapoptotic Bax and SARM, imbalance of Bcl-2/Bax in the mitochondria, induction of cytosolic cytochrome c and activation of caspase-9 and -3, all of which led to disequilibrium between life and death of macrophages.	sagopilone	0-3	sterile alpha and TIR motif containing 1	Homo sapiens	62-66	
24786833-7	2014	SAG knockdown caused the accumulation of proapoptotic Bax and SARM, imbalance of Bcl-2/Bax in the mitochondria, induction of cytosolic cytochrome c and activation of caspase-9 and -3, all of which led to disequilibrium between life and death of macrophages.	sagopilone	0-3	BCL2 apoptosis regulator	Homo sapiens	81-86	
24786833-7	2014	SAG knockdown caused the accumulation of proapoptotic Bax and SARM, imbalance of Bcl-2/Bax in the mitochondria, induction of cytosolic cytochrome c and activation of caspase-9 and -3, all of which led to disequilibrium between life and death of macrophages.	sagopilone	0-3	BCL2 associated X, apoptosis regulator	Homo sapiens	87-90	
24786833-7	2014	SAG knockdown caused the accumulation of proapoptotic Bax and SARM, imbalance of Bcl-2/Bax in the mitochondria, induction of cytosolic cytochrome c and activation of caspase-9 and -3, all of which led to disequilibrium between life and death of macrophages.	sagopilone	0-3	cytochrome c, somatic	Homo sapiens	135-147	
24786833-7	2014	SAG knockdown caused the accumulation of proapoptotic Bax and SARM, imbalance of Bcl-2/Bax in the mitochondria, induction of cytosolic cytochrome c and activation of caspase-9 and -3, all of which led to disequilibrium between life and death of macrophages.	sagopilone	0-3	caspase 9	Homo sapiens	166-182	
24786833-8	2014	In contrast, SAG-overexpressing macrophages challenged with PAMPs exhibited upregulation of protumorigenic cytokines (IL-1beta, IL-6 and TNF-alpha), and downregulation of antitumorigenic cytokine (IL-12p40) and anti-inflammatory cytokine (IL-10).	sagopilone	13-16	interleukin 1 beta	Homo sapiens	118-126	
24786833-8	2014	In contrast, SAG-overexpressing macrophages challenged with PAMPs exhibited upregulation of protumorigenic cytokines (IL-1beta, IL-6 and TNF-alpha), and downregulation of antitumorigenic cytokine (IL-12p40) and anti-inflammatory cytokine (IL-10).	sagopilone	13-16	interleukin 6	Homo sapiens	128-132	
24786833-8	2014	In contrast, SAG-overexpressing macrophages challenged with PAMPs exhibited upregulation of protumorigenic cytokines (IL-1beta, IL-6 and TNF-alpha), and downregulation of antitumorigenic cytokine (IL-12p40) and anti-inflammatory cytokine (IL-10).	sagopilone	13-16	tumor necrosis factor	Homo sapiens	137-146	
24786833-8	2014	In contrast, SAG-overexpressing macrophages challenged with PAMPs exhibited upregulation of protumorigenic cytokines (IL-1beta, IL-6 and TNF-alpha), and downregulation of antitumorigenic cytokine (IL-12p40) and anti-inflammatory cytokine (IL-10).	sagopilone	13-16	interleukin 10	Homo sapiens	239-244