Title : Anti-inflammatory effects of short chain fatty acids in IFN-gamma-stimulated RAW 264.7 murine macrophage cells: involvement of NF-kappaB and ERK signaling pathways.

Pub. Date : 2007 Jan

PMID : 17161819






4 Functional Relationships(s)
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1 In this study, three types of short chain fatty acids (sodium butyrate (NaB), sodium phenylbutyrate (NaPB), sodium phenylacetate (NaPA)) were found to have anti-inflammatory effects in IFN-gamma-stimulated RAW 264.7 cells. Acecainide interferon gamma Mus musculus
2 Their potency as anti-inflammatory agents was in the order of NaB>NaPB>NaPA. Acecainide N-ethylmaleimide sensitive fusion protein attachment protein beta Mus musculus
3 The potency of NF-kappaB and ERK inhibition was also in the order of NaB>NaPB>NaPA. Acecainide nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
4 The potency of NF-kappaB and ERK inhibition was also in the order of NaB>NaPB>NaPA. Acecainide mitogen-activated protein kinase 1 Mus musculus