Protein Name N-ethylmaleimide sensitive fusion protein attachment protein beta
Organism Mus musculus
Gene ID 17957
Gene Symbol

Napb

UniProt P28663 (SNAB_MOUSE)
Relationships Total Number of functionally related compound(s) : 21
Total Number of Articles : 11
Description

N-ethylmaleimide sensitive fusion protein attachment protein beta

Gene Summary

Enables syntaxin binding activity. Involved in regulation of synaptic vesicle priming. Acts upstream of or within SNARE complex disassembly and glutamatergic synaptic transmission. Located in myelin sheath. Part of synaptobrevin 2-SNAP-25-syntaxin-1a complex. Is active in glutamatergic synapse. Is expressed in central nervous system; liver; peripheral nervous system ganglion; retina nuclear layer; and testis. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 107. Orthologous to human NAPB (NSF attachment protein beta). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • beta-soluble NSF attachment protein
  • N-ethylmaleimide-sensitive factor attachment protein beta
  • SNAP-beta
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Properties