Title : Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.

Pub. Date : 2005 Jul

PMID : 15774489






7 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade. microcystin AKT serine/threonine kinase 1 Homo sapiens
2 Inhibition of Akt, p38 and JNK activation led to a reduced proliferation of microcystin-transformed cells. microcystin AKT serine/threonine kinase 1 Homo sapiens
3 Inhibition of Akt, p38 and JNK activation led to a reduced proliferation of microcystin-transformed cells. microcystin mitogen-activated protein kinase 14 Homo sapiens
4 Inhibition of Akt, p38 and JNK activation led to a reduced proliferation of microcystin-transformed cells. microcystin mitogen-activated protein kinase 8 Homo sapiens
5 This implies that the constitutive activation of Akt and the p38, JNK of MAPK pathways in microcystin-transformed cells may be the mechanism by which this important external factor acts in the carcinogenesis of CRC. microcystin AKT serine/threonine kinase 1 Homo sapiens
6 This implies that the constitutive activation of Akt and the p38, JNK of MAPK pathways in microcystin-transformed cells may be the mechanism by which this important external factor acts in the carcinogenesis of CRC. microcystin mitogen-activated protein kinase 14 Homo sapiens
7 This implies that the constitutive activation of Akt and the p38, JNK of MAPK pathways in microcystin-transformed cells may be the mechanism by which this important external factor acts in the carcinogenesis of CRC. microcystin mitogen-activated protein kinase 8 Homo sapiens