Title : Inhibition of constitutively activated nuclear factor-kappaB radiosensitizes human melanoma cells.

Pub. Date : 2004 Aug

PMID : 15299081






2 Functional Relationships(s)
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1 To test this, MeWo and A375 melanoma cells were exposed to the MEK inhibitor PD184352. 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide mitogen-activated protein kinase kinase 7 Homo sapiens
2 Treatment with PD184352 partially reversed NF-kappaB activity but did not impart radiation sensitivity to these cells. 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide nuclear factor kappa B subunit 1 Homo sapiens