Title : Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive.

Pub. Date : 2002 Feb

PMID : 11864911






1 Functional Relationships(s)
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1 Adenovirus-mediated expression of "dominant-negative" Chk1 (but not dominant-negative Chk2) and the Chk1 inhibitor UCN-01 abrogated the S-phase delay elicited by low doses of BPDE. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide urocortin Homo sapiens