Pub. Date : 2019 Dec
PMID : 31479709
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Modulation of FLT3 through decitabine-activated C/EBPa-PU.1 signal pathway in FLT3-ITD positive cells. | Decitabine | fms related receptor tyrosine kinase 3 | Homo sapiens |
2 | Modulation of FLT3 through decitabine-activated C/EBPa-PU.1 signal pathway in FLT3-ITD positive cells. | Decitabine | fms related receptor tyrosine kinase 3 | Homo sapiens |
3 | This study aimed to examine the effect of decitabine (DAC) on FLT3-ITD positive AML. | Decitabine | fms related receptor tyrosine kinase 3 | Homo sapiens |
4 | This study aimed to examine the effect of decitabine (DAC) on FLT3-ITD positive AML. | Decitabine | fms related receptor tyrosine kinase 3 | Homo sapiens |
5 | In our study, we found that expression of FLT3 and its downstream targets was decreased in FLT3-ITD mutant cell lines treated with DAC. | Decitabine | fms related receptor tyrosine kinase 3 | Homo sapiens |
6 | In our study, we found that expression of FLT3 and its downstream targets was decreased in FLT3-ITD mutant cell lines treated with DAC. | Decitabine | fms related receptor tyrosine kinase 3 | Homo sapiens |
7 | These findings indicated that DAC upregulated PU.1 to induce downregulation of FLT3 to trigger apoptosis. | Decitabine | fms related receptor tyrosine kinase 3 | Homo sapiens |