PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31479709-0 2019 Modulation of FLT3 through decitabine-activated C/EBPa-PU.1 signal pathway in FLT3-ITD positive cells. Decitabine 27-37 fms related receptor tyrosine kinase 3 Homo sapiens 14-18 31479709-0 2019 Modulation of FLT3 through decitabine-activated C/EBPa-PU.1 signal pathway in FLT3-ITD positive cells. Decitabine 27-37 fms related receptor tyrosine kinase 3 Homo sapiens 78-82 31479709-2 2019 This study aimed to examine the effect of decitabine (DAC) on FLT3-ITD positive AML. Decitabine 42-52 fms related receptor tyrosine kinase 3 Homo sapiens 62-66 31479709-2 2019 This study aimed to examine the effect of decitabine (DAC) on FLT3-ITD positive AML. Decitabine 54-57 fms related receptor tyrosine kinase 3 Homo sapiens 62-66 31479709-3 2019 In our study, we found that expression of FLT3 and its downstream targets was decreased in FLT3-ITD mutant cell lines treated with DAC. Decitabine 131-134 fms related receptor tyrosine kinase 3 Homo sapiens 42-46 31479709-3 2019 In our study, we found that expression of FLT3 and its downstream targets was decreased in FLT3-ITD mutant cell lines treated with DAC. Decitabine 131-134 fms related receptor tyrosine kinase 3 Homo sapiens 91-95 31479709-8 2019 These findings indicated that DAC upregulated PU.1 to induce downregulation of FLT3 to trigger apoptosis. Decitabine 30-33 fms related receptor tyrosine kinase 3 Homo sapiens 79-83