Title : Abiraterone acetate: a promising drug for the treatment of castration-resistant prostate cancer.

Pub. Date : 2010 May

PMID : 20465382






1 Functional Relationships(s)
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1 Abiraterone acetate (CB7630), a pregnenolone analog, is an orally administered small molecule that irreversibly inhibits a rate-limiting enzyme in androgen biosynthesis, CYP17, and blocks the synthesis of androgens in the testes, adrenal glands and prostate without causing adrenal insufficiency. Pregnenolone cytochrome P450 family 17 subfamily A member 1 Homo sapiens