PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20465382-1 2010 Abiraterone acetate (CB7630), a pregnenolone analog, is an orally administered small molecule that irreversibly inhibits a rate-limiting enzyme in androgen biosynthesis, CYP17, and blocks the synthesis of androgens in the testes, adrenal glands and prostate without causing adrenal insufficiency. Pregnenolone 32-44 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 170-175