Pub. Date : 2005 Feb
PMID : 15780952
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | IL-1-induced receptor activator of NF-kappa B ligand in human periodontal ligament cells involves ERK-dependent PGE2 production. | Dinoprostone | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | IL-1alpha activated ERK phosphorylation and PD98059 greatly inhibited both COX-2 mRNA expression and PGE(2) production induced by IL-1alpha in PDL cells. | Dinoprostone | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | These results suggest that IL-1alpha stimulates osteoclast formation by increasing the expression level of RANKL versus OPG via ERK-dependent PGE2 production in PDL cells. | Dinoprostone | mitogen-activated protein kinase 1 | Homo sapiens |