Title : Activation of c-Raf kinase by ultraviolet light. Regulation by retinoids.

Pub. Date : 2002 Jun 28

PMID : 11971897






1 Functional Relationships(s)
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1 Thus, retinoids bound c-Raf with high affinity, priming the molecule for UV/reactive oxygen species-mediated changes of the CRD that set off GTP-Ras interaction and, in context with an appropriate phosphorylation pattern, lead to full phosphotransferase capacity. Guanosine Triphosphate Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens