PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11971897-8 2002 Thus, retinoids bound c-Raf with high affinity, priming the molecule for UV/reactive oxygen species-mediated changes of the CRD that set off GTP-Ras interaction and, in context with an appropriate phosphorylation pattern, lead to full phosphotransferase capacity. Guanosine Triphosphate 141-144 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 22-27