Alanine

serpin family C member 1 ; Homo sapiens







13 Article(s)
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1 24068708 The allosteric mechanism of activation of antithrombin as an inhibitor of factor IXa and factor Xa: heparin-independent full activation through mutations adjacent to helix D. 2013 Nov 22 2
2 16884719 Allosteric activation of antithrombin is independent of charge neutralization or reversal in the heparin binding site. 2006 Aug 21 1
3 12578831 Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol. 2003 Apr 25 1
4 10037709 Exosites 1 and 2 are essential for protection of fibrin-bound thrombin from heparin-catalyzed inhibition by antithrombin and heparin cofactor II. 1999 Mar 5 2
5 9493570 Antithrombin cambridge II (Ala384Ser): clinical, functional and haplotype analysis of 18 families. 1998 Feb 1
6 8026575 Proteolytically cleaved mutant antithrombin-Hamilton has high stability to denaturation characteristic of wild type inhibitor serpins. 1994 Jul 4 2
7 8176841 [Heparan sulfate proteoglycan of endothelial cells: homocysteine suppresses anticoagulant active heparan sulfate in cultured endothelial cells]. 1994 Apr 1
8 8376590 Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells. 1993 Sep 1
9 1604438 A useful restriction analysis for the determination of human antithrombin III variants with mutations from Ala 382 to Ala 384. 1992 Jan 1 2
10 1911389 Antithrombin Glasgow II: alanine 382 to threonine mutation in the serpin P12 position, resulting in a substrate reaction with thrombin. 1991 Sep 1
11 1690736 Hydrophobic residues 382-386 of antithrombin III, Ala-Ala-Ala-Ser-Thr, serve as the epitope for an antibody which facilitates hydrolysis of the inhibitor by thrombin. 1990 Mar 25 1
12 3179438 Antithrombin-III-Hamilton: a gene with a point mutation (guanine to adenine) in codon 382 causing impaired serine protease reactivity. 1988 Nov 3
13 3305015 Probing the heparin-binding domain of human antithrombin III with V8 protease. 1987 Sep 1 2