Pub. Date : 2006 Aug 21
PMID : 16884719
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We investigate the hypothesis that heparin activates antithrombin (AT) by relieving electrostatic strain within helix D. Mutation of residues K125 and R129 to either Ala or Glu abrogated heparin binding, but did not activate AT towards inhibition of factors IXa or Xa. | Alanine | serpin family C member 1 | Homo sapiens |