Title : Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol.

Pub. Date : 2003 Apr 25

PMID : 12578831






1 Functional Relationships(s)
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Protein Name
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1 Replacement of His-334 in alpha(1)-antitrypsin by a serine or alanine at pH 7.4 results in the same polymerization and loop-peptide acceptance observed with antithrombin at low pH. Alanine serpin family C member 1 Homo sapiens