10 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 32223238 | Multistep Binding of the Non-Steroidal Inhibitors Orteronel and Seviteronel to Human Cytochrome P450 17A1 and Relevance to Inhibition of Enzyme Activity. | 2020 Jun 25 | 1 |
2 | 33004739 | CYP17 inhibitors improve the prognosis of metastatic castration-resistant prostate cancer patients: A meta-analysis of published trials. | 2020 Sep | 1 |
3 | 28373265 | Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1. | 2017 Jun | 1 |
4 | 26971992 | Incidence and relative risk of adverse events of special interest in patients with castration resistant prostate cancer treated with CYP-17 inhibitors: A meta-analysis of published trials. | 2016 May | 1 |
5 | 25560485 | CYP17A1 inhibitors in castration-resistant prostate cancer. | 2015 Mar | 1 |
6 | 24799061 | Orteronel for the treatment of prostate cancer. | 2014 Apr | 1 |
7 | 23371447 | Targeting the adrenal gland in castration-resistant prostate cancer: a case for orteronel, a selective CYP-17 17,20-lyase inhibitor. | 2013 Apr | 2 |
8 | 23856460 | Effect of an investigational CYP17A1 inhibitor, orteronel (TAK-700), on estrogen- and corticoid-synthesis pathways in hypophysectomized female rats and on the serum estradiol levels in female cynomolgus monkeys. | 2013 Nov | 2 |
9 | 24314737 | [Prostate cancer and new hormonal treatments: mechanism of action and main clinical results]. | 2013 Oct | 1 |
10 | 22249003 | Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys. | 2012 Apr | 3 |