orteronel

cytochrome P450 family 17 subfamily A member 1 ; Homo sapiens







10 Article(s)
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1 32223238 Multistep Binding of the Non-Steroidal Inhibitors Orteronel and Seviteronel to Human Cytochrome P450 17A1 and Relevance to Inhibition of Enzyme Activity. 2020 Jun 25 1
2 33004739 CYP17 inhibitors improve the prognosis of metastatic castration-resistant prostate cancer patients: A meta-analysis of published trials. 2020 Sep 1
3 28373265 Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1. 2017 Jun 1
4 26971992 Incidence and relative risk of adverse events of special interest in patients with castration resistant prostate cancer treated with CYP-17 inhibitors: A meta-analysis of published trials. 2016 May 1
5 25560485 CYP17A1 inhibitors in castration-resistant prostate cancer. 2015 Mar 1
6 24799061 Orteronel for the treatment of prostate cancer. 2014 Apr 1
7 23371447 Targeting the adrenal gland in castration-resistant prostate cancer: a case for orteronel, a selective CYP-17 17,20-lyase inhibitor. 2013 Apr 2
8 23856460 Effect of an investigational CYP17A1 inhibitor, orteronel (TAK-700), on estrogen- and corticoid-synthesis pathways in hypophysectomized female rats and on the serum estradiol levels in female cynomolgus monkeys. 2013 Nov 2
9 24314737 [Prostate cancer and new hormonal treatments: mechanism of action and main clinical results]. 2013 Oct 1
10 22249003 Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys. 2012 Apr 3