Pregnenolone

cytochrome P450 family 17 subfamily A member 1 ; Homo sapiens







64 Article(s)
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Pub. Year
#Total Relationships
51 12446594 Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species. 2002 Dec 1
52 12573809 Androgen biosynthesis from cholesterol to DHEA. 2002 Dec 30 1
53 10824109 Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone. 2000 Jun 3
54 9927319 Dehydroepiandrosterone: biosynthesis and metabolism in the brain. 1999 Feb 1
55 9768686 Adrenarche results from development of a 3beta-hydroxysteroid dehydrogenase-deficient adrenal reticularis. 1998 Oct 2
56 9888582 The molecular basis of isolated 17,20 lyase deficiency. 1998 Aug-Nov 6
57 9890062 Early steps in androgen biosynthesis: from cholesterol to DHEA. 1998 Apr 1
58 7578007 Mechanistic kinship between hydroxylation and desaturation reactions: acyl-carbon bond cleavage promoted by pig and human CYP17 (P-450(17)alpha; 17 alpha-hydroxylase-17,20-lyase). 1995 Oct 31 2
59 7893148 The role of cytochrome b5 in the biosynthesis of androgens by human P450c17. 1995 Mar 10 1
60 8948449 Modulation of the activity of human 17 alpha-hydroxylase-17,20-lyase (CYP17) by cytochrome b5: endocrinological and mechanistic implications. 1995 Jun 15 1
61 8323292 Expression in Escherichia coli of functional cytochrome P450c17 lacking its hydrophobic amino-terminal signal anchor. 1993 Jul 1
62 8325965 Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase. 1993 Jul 1
63 8396144 Expression and purification of functional human 17 alpha-hydroxylase/17,20-lyase (P450c17) in Escherichia coli. Use of this system for study of a novel form of combined 17 alpha-hydroxylase/17,20-lyase deficiency. 1993 Sep 15 4
64 2555382 Molecular characterization of a Leydig cell tumor presenting as congenital adrenal hyperplasia. 1989 Dec 1