Title : Modulation of the activity of human 17 alpha-hydroxylase-17,20-lyase (CYP17) by cytochrome b5: endocrinological and mechanistic implications.

Pub. Date : 1995 Jun 15

PMID : 8948449






1 Functional Relationships(s)
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1 Like the pig CYP17, the human CYP17 also catalysed the cytochrome b5-dependent direct cleavage of pregnenolone into the delta 5,16-steroid, but unlike it the human enzyme did not cleave progesterone at all. Pregnenolone cytochrome P450 family 17 subfamily A member 1 Homo sapiens