Simvastatin

phosphatase and tensin homolog ; Homo sapiens







10 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 33742146 Kinome-wide analysis of the effect of statins in colorectal cancer. 2021 Jun 1
2 29208461 Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway. 2018 Jan 15 5
3 29385181 Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy. 2018 1
4 29568880 Simvastatin induces apoptosis in PTEN‑haploinsufficient lipoma cells. 2018 Jun 6
5 26565813 Simvastatin-induced breast cancer cell death and deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by metabolic products of the mevalonate pathway. 2016 Jan 19 2
6 24535918 RhoA-mediated inhibition of vascular endothelial cell mobility: positive feedback through reduced cytosolic p21 and p27. 2014 Oct 1
7 23973711 Statin induces inhibition of triple negative breast cancer (TNBC) cells via PI3K pathway. 2013 Sep 20 4
8 20060890 Simvastatin induces derepression of PTEN expression via NFkappaB to inhibit breast cancer cell growth. 2010 May 4
9 18065496 Regulation of the PTEN promoter by statins and SREBP. 2008 Apr 1 1
10 15776112 Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts. 2005 Apr 1