Tamoxifen

phosphatase and tensin homolog ; Homo sapiens







19 Article(s)
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1 34978016 PTEN promoter methylation predicts 10-year prognosis in hormone receptor-positive early breast cancer patients who received adjuvant tamoxifen endocrine therapy. 2022 Feb 4
2 31604073 Knockdown of PTEN decreases expression of estrogen receptor β and tamoxifen sensitivity of human breast cancer cells. 2020 Jan 4
3 33173749 CD63+ Cancer-Associated Fibroblasts Confer Tamoxifen Resistance to Breast Cancer Cells through Exosomal miR-22. 2020 Nov 1
4 33318536 Upregulation of PI3K/AKT/PTEN pathway is correlated with glucose and glutamine metabolic dysfunction during tamoxifen resistance development in MCF-7 cells. 2020 Dec 14 5
5 30573703 The ER-alpha mutation Y537S confers Tamoxifen-resistance via enhanced mitochondrial metabolism, glycolysis and Rho-GDI/PTEN signaling: Implicating TIGAR in somatic resistance to endocrine therapy. 2018 Dec 20 1
6 26418898 Induction of methionine adenosyltransferase 2A in tamoxifen-resistant breast cancer cells. 2016 Mar 22 1
7 25882671 Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion. 2015 1
8 24853176 MGMT promoter hypermethylation and K-RAS, PTEN and TP53 mutations in tamoxifen-exposed and non-exposed endometrial cancer cases. 2014 Jun 10 1
9 23515291 Insulin-like growth factor binding protein 2 (IGFBP-2) promotes growth and survival of breast epithelial cells: novel regulation of the estrogen receptor. 2013 May 1
10 22892847 The impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen treatment in breast cancer patients. 2012 Oct 4
11 21170675 Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells. 2011 Nov 2
12 21674849 PTEN protein expression in postmenopausal steroid receptor positive early breast cancer patients treated with adjuvant tamoxifen. 2011 Jan-Mar 2
13 19435893 Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer. 2009 May 15 2
14 18500270 Clinicopathological and molecular analysis of endometrial carcinoma associated with tamoxifen. 2008 Aug 2
15 18814240 Early aberrant insulin-like growth factor signaling in the progression to endometrial carcinoma is augmented by tamoxifen. 2008 Dec 15 1
16 17914589 Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expression. 2007 Nov 1
17 15475931 Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen. 2005 Feb 4
18 15589576 Molecular genetic characterization of tamoxifen-associated endometrial cancer. 2005 Jan 1
19 12530022 PTEN expression in tamoxifen-associated endometrial cancers. 2002 Sep-Oct 4