Pub. Date : 2012 Oct
PMID : 22892847
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen treatment in breast cancer patients. | Tamoxifen | phosphatase and tensin homolog | Homo sapiens |
| 2 | The primary aim of this study was to investigate the impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen by analyzing loss of heterozygosity (LOH) and immunohystochemical expression of PTEN in 49 primary breast carcinomas of patients treated with tamoxifen as the only adjuvant therapy. | Tamoxifen | phosphatase and tensin homolog | Homo sapiens |
| 3 | The primary aim of this study was to investigate the impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen by analyzing loss of heterozygosity (LOH) and immunohystochemical expression of PTEN in 49 primary breast carcinomas of patients treated with tamoxifen as the only adjuvant therapy. | Tamoxifen | phosphatase and tensin homolog | Homo sapiens |
| 4 | In summary, our results imply that LOH of PTEN could be used as a good prognostic characteristic for the outcome of breast cancer patients treated with tamoxifen. | Tamoxifen | phosphatase and tensin homolog | Homo sapiens |