| 1 |
34971590 | Off-target lipid metabolism disruption by the mouse constitutive androstane receptor ligand TCPOBOP in humanized mice. | 2022 Mar |
3 |
| 2 |
35305226 | Promotion of NR1I3-mediated liver growth is accompanied by STAT3 activation. | 2022 May |
1 |
| 3 |
33643822 | Gadd45b is required in part for the anti-obesity effect of constitutive androstane receptor (CAR). | 2021 Feb |
2 |
| 4 |
33777678 | Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation. | 2021 Mar |
3 |
| 5 |
34097921 | Xenobiotic Receptor CAR Is Highly Induced in Psoriasis and Promotes Keratinocyte Proliferation. | 2021 Dec |
1 |
| 6 |
34502180 | Activation of the Constitutive Androstane Receptor Inhibits Leukocyte Adhesiveness to Dysfunctional Endothelium. | 2021 Aug 27 |
1 |
| 7 |
32123963 | Array-based Western-blotting reveals spatial differences in hepatic signaling and metabolism following CAR activation. | 2020 Apr |
1 |
| 8 |
29888801 | TCPOBOP-Induced Hepatomegaly and Hepatocyte Proliferation are Attenuated by Combined Disruption of MET and EGFR Signaling. | 2019 Apr |
4 |
| 9 |
30442521 | Constitutive androstane receptor and pregnane X receptor cooperatively ameliorate DSS-induced colitis. | 2019 Feb |
1 |
| 10 |
30620001 | Constitutive Androstane Receptor Differentially Regulates Bile Acid Homeostasis in Mouse Models of Intrahepatic Cholestasis. | 2019 Jan |
2 |
| 11 |
31394088 | Promotion of liver growth by CAR is accompanied by Akt pathway activation and FoxM1-Nedd4-mediated repression of PTEN. | 2019 Sep 15 |
2 |
| 12 |
29351922 | Activation of Constitutive Androstane Receptor Ameliorates Renal Ischemia-Reperfusion-Induced Kidney and Liver Injury. | 2018 Mar |
2 |
| 13 |
29617930 | Impact of CAR Agonist Ligand TCPOBOP on Mouse Liver Chromatin Accessibility. | 2018 Jul 1 |
4 |
| 14 |
29893953 | Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes. | 2018 Oct 1 |
1 |
| 15 |
30201494 | High Frequency of β-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist. | 2018 Nov |
2 |
| 16 |
28095325 | Peroxisome proliferator-activated receptor γ activation inhibits liver growth through miR-122-mediated downregulation of cMyc. | 2017 Feb 15 |
2 |
| 17 |
28903501 | Sex-Differential Responses of Tumor Promotion-Associated Genes and Dysregulation of Novel Long Noncoding RNAs in Constitutive Androstane Receptor-Activated Mouse Liver. | 2017 Sep 1 |
2 |
| 18 |
26984780 | Activation of Constitutive Androstane Receptor (CAR) in Mice Results in Maintained Biliary Excretion of Bile Acids Despite a Marked Decrease of Bile Acids in Liver. | 2016 Jun |
2 |
| 19 |
27080131 | Bioinformatic analysis of microRNA networks following the activation of the constitutive androstane receptor (CAR) in mouse liver. | 2016 Sep |
2 |
| 20 |
27413110 | Editor's Highlight: Neonatal Activation of the Xenobiotic-Sensors PXR and CAR Results in Acute and Persistent Down-regulation of PPARα-Signaling in Mouse Liver. | 2016 Oct |
1 |
| 21 |
27530923 | Constitutive androstane receptor activation evokes the expression of glycolytic genes. | 2016 Sep 23 |
4 |
| 22 |
25949234 | Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium. | 2015 |
3 |
| 23 |
26171734 | Xenosensor CAR mediates down-regulation of miR-122 and up-regulation of miR-122 targets in the liver. | 2015 Oct 1 |
2 |
| 24 |
26179144 | Isoform-Specific Regulation of Mouse Carboxylesterase Expression and Activity by Prototypical Transcriptional Activators. | 2015 Dec |
1 |
| 25 |
24194512 | Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters. | 2014 Jan |
1 |
| 26 |
24769335 | CAR-mediated repression of Foxo1 transcriptional activity regulates the cell cycle inhibitor p21 in mouse livers. | 2014 Jul 3 |
4 |
| 27 |
25052003 | Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat. | 2014 |
2 |
| 28 |
23578392 | The time point of β-catenin knockout in hepatocytes determines their response to xenobiotic activation of the constitutive androstane receptor. | 2013 Jun 7 |
4 |
| 29 |
23626729 | Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice. | 2013 |
2 |
| 30 |
23660342 | Tissue distribution, ontogeny, and chemical induction of aldo-keto reductases in mice. | 2013 Aug |
1 |
| 31 |
21827731 | SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism. | 2012 Jan |
1 |
| 32 |
21839802 | Treatment with a constitutive androstane receptor ligand ameliorates the signs of preeclampsia in high-fat diet-induced obese pregnant mice. | 2012 Jan 2 |
2 |
| 33 |
22488010 | Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver. | 2012 Oct |
4 |
| 34 |
21415305 | Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane receptor. | 2011 Jun |
1 |
| 35 |
21965327 | Gadd45β is an inducible coactivator of transcription that facilitates rapid liver growth in mice. | 2011 Nov |
1 |
| 36 |
20185760 | Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3). | 2010 Apr |
1 |
| 37 |
20404936 | Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B. | 2010 Apr 12 |
5 |
| 38 |
20516253 | Histone deacetylase inhibitors induce cytochrome P450 2B by activating nuclear receptor constitutive androstane receptor. | 2010 Sep |
1 |
| 39 |
20547735 | Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. | 2010 Sep |
2 |
| 40 |
19041682 | Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR). | 2009 Feb 4 |
1 |
| 41 |
19196849 | Constitutive androstane receptor-mediated changes in bile acid composition contributes to hepatoprotection from lithocholic acid-induced liver injury in mice. | 2009 May |
2 |
| 42 |
19359405 | Regulation of tissue-specific carboxylesterase expression by pregnane x receptor and constitutive androstane receptor. | 2009 Jul |
2 |
| 43 |
19617349 | The constitutive androstane receptor is an anti-obesity nuclear receptor that improves insulin sensitivity. | 2009 Sep 18 |
2 |
| 44 |
18281256 | Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR. | 2008 May |
2 |
| 45 |
17314319 | Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes. | 2007 May |
4 |
| 46 |
17627975 | Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport. | 2007 Oct |
4 |
| 47 |
17948939 | Constitutive androstane receptor agonist, TCPOBOP, attenuates steatohepatitis in the methionine choline-deficient diet-fed mouse. | 2007 Nov 14 |
4 |
| 48 |
16749864 | Activation of human CYP2C9 promoter and regulation by CAR and PXR in mouse liver. | 2006 May-Jun |
1 |
| 49 |
16799968 | Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. | 2006 Jul |
1 |
| 50 |
16929008 | Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica). | 2006 Nov |
1 |