Title : Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica).

Pub. Date : 2006 Nov

PMID : 16929008






1 Functional Relationships(s)
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1 As for exogenous chemicals, the seal CAR was transactivated by a human CAR agonist, 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime), but not by a mouse CAR agonist, (1,4-bis[2-(3,5-dichloropyridyloxy)]benzene). 1,4-bis(2-(3,5-dichloropyridyloxy))benzene nuclear receptor subfamily 1, group I, member 3 Mus musculus