| 1 |
34452919 | Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors. | 2021 Aug |
1 |
| 2 |
32131593 | Molecular Mechanism of ISC Iron-Sulfur Cluster Biogenesis Revealed by High-Resolution Native Mass Spectrometry. | 2020 Apr 1 |
1 |
| 3 |
30817134 | Analysis of the Cellular Roles of MOCS3 Identifies a MOCS3-Independent Localization of NFS1 at the Tips of the Centrosome. | 2019 Apr 2 |
2 |
| 4 |
30975898 | Mechanism of frataxin "bypass" in human iron-sulfur cluster biosynthesis with implications for Friedreich's ataxia. | 2019 Jun 7 |
2 |
| 5 |
31101807 | Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism. | 2019 May 17 |
1 |
| 6 |
31395877 | Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin. | 2019 Aug 8 |
1 |
| 7 |
29090418 | Chemical shift assignment of a thermophile frataxin. | 2018 Apr |
2 |
| 8 |
29782976 | LdIscU is a [2Fe-2S] scaffold protein which interacts with LdIscS and its expression is modulated by Fe-S proteins in Leishmania donovani. | 2018 Sep |
1 |
| 9 |
28271877 | The N-Terminus of Iron-Sulfur Cluster Assembly Factor ISD11 Is Crucial for Subcellular Targeting and Interaction with l-Cysteine Desulfurase NFS1. | 2017 Mar 28 |
1 |
| 10 |
28323419 | The Role of SufS Is Restricted to Fe-S Cluster Biosynthesis in Escherichia coli. | 2017 Apr 11 |
2 |
| 11 |
28548666 | Zinc and the iron donor frataxin regulate oligomerization of the scaffold protein to form new Fe-S cluster assembly centers. | 2017 Jun 21 |
1 |
| 12 |
28634302 | Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions. | 2017 Jul 3 |
1 |
| 13 |
28766335 | Functional Complementation Studies Reveal Different Interaction Partners of Escherichia coli IscS and Human NFS1. | 2017 Aug 29 |
3 |
| 14 |
28882199 | Defining the Architecture of the Core Machinery for the Assembly of Fe-S Clusters in Human Mitochondria. | 2017 |
1 |
| 15 |
29168506 | NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis. | 2017 Nov 30 |
2 |
| 16 |
26842892 | Protection of scaffold protein Isu from degradation by the Lon protease Pim1 as a component of Fe-S cluster biogenesis regulation. | 2016 Apr 1 |
1 |
| 17 |
26941001 | Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: THE SUB-COMPLEX FORMED BY THE IRON DONOR, Yfh1 PROTEIN, AND THE SCAFFOLD, Isu1 PROTEIN. | 2016 May 6 |
1 |
| 18 |
27427956 | The Eukaryotic-Specific ISD11 Is a Complex-Orphan Protein with Ability to Bind the Prokaryotic IscS. | 2016 |
1 |
| 19 |
27519411 | Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery. | 2016 Sep 30 |
1 |
| 20 |
25398879 | Fe-S cluster biogenesis in isolated mammalian mitochondria: coordinated use of persulfide sulfur and iron and requirements for GTP, NADH, and ATP. | 2015 Jan 2 |
3 |
| 21 |
25597503 | Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols. | 2015 Jan 19 |
3 |
| 22 |
25688831 | Ferredoxin, in conjunction with NADPH and ferredoxin-NADP reductase, transfers electrons to the IscS/IscU complex to promote iron-sulfur cluster assembly. | 2015 Sep |
1 |
| 23 |
26016518 | Frataxin Accelerates [2Fe-2S] Cluster Formation on the Human Fe-S Assembly Complex. | 2015 Jun 30 |
1 |
| 24 |
26342079 | Mapping Key Residues of ISD11 Critical for NFS1-ISD11 Subcomplex Stability: IMPLICATIONS IN THE DEVELOPMENT OF MITOCHONDRIAL DISORDER, COXPD19. | 2015 Oct 23 |
1 |
| 25 |
24573684 | The presence of multiple cellular defects associated with a novel G50E iron-sulfur cluster scaffold protein (ISCU) mutation leads to development of mitochondrial myopathy. | 2014 Apr 11 |
1 |
| 26 |
24971490 | Human frataxin activates Fe-S cluster biosynthesis by facilitating sulfur transfer chemistry. | 2014 Aug 5 |
1 |
| 27 |
25044349 | The scaffold protein IscU retains a structured conformation in the Fe-S cluster assembly complex. | 2014 Jul 21 |
1 |
| 28 |
25062827 | Reactive oxygen species regulates expression of iron-sulfur cluster assembly protein IscS of Leishmania donovani. | 2014 Oct |
2 |
| 29 |
23593335 | The L-cysteine desulfurase NFS1 is localized in the cytosol where it provides the sulfur for molybdenum cofactor biosynthesis in humans. | 2013 |
5 |
| 30 |
23814038 | Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes. | 2013 Nov 15 |
1 |
| 31 |
23940031 | Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the iron-sulfur cluster scaffold protein (ISCU). | 2013 Oct 4 |
1 |
| 32 |
23946486 | Binding of the chaperone Jac1 protein and cysteine desulfurase Nfs1 to the iron-sulfur cluster scaffold Isu protein is mutually exclusive. | 2013 Oct 4 |
2 |
| 33 |
22294093 | Competing pathways control host resistance to virus via tRNA modification and programmed ribosomal frameshifting. | 2012 Jan 31 |
2 |
| 34 |
22609301 | The role of mitochondria in cellular iron-sulfur protein biogenesis and iron metabolism. | 2012 Sep |
1 |
| 35 |
22689995 | Cysteine desulfurase Nfs1 and Pim1 protease control levels of Isu, the Fe-S cluster biogenesis scaffold. | 2012 Jun 26 |
1 |
| 36 |
20957368 | Expression, purification, and characterization of an iron chaperon protein CyaY from Acidithiobacillus ferrooxidans. | 2011 Mar |
1 |
| 37 |
21671584 | Friedreich's ataxia variants I154F and W155R diminish frataxin-based activation of the iron-sulfur cluster assembly complex. | 2011 Jul 26 |
1 |
| 38 |
21926174 | Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent manner. | 2011 Nov 25 |
1 |
| 39 |
20404999 | Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions. | 2010 Apr 13 |
9 |
| 40 |
20405048 | Synopsis. Multiple sulfur acceptors dock at IscS. | 2010 Apr 13 |
1 |
| 41 |
20889968 | Normal and Friedreich ataxia cells express different isoforms of frataxin with complementary roles in iron-sulfur cluster assembly. | 2010 Dec 3 |
2 |
| 42 |
19146390 | Iron-sulfur cluster biosynthesis: functional characterization of the N- and C-terminal domains of human NFU. | 2009 Feb 10 |
1 |
| 43 |
19454487 | Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. | 2009 Aug 15 |
1 |
| 44 |
19491103 | Oligomeric yeast frataxin drives assembly of core machinery for mitochondrial iron-sulfur cluster synthesis. | 2009 Aug 14 |
1 |
| 45 |
19720832 | Dual targeting of Nfs1 and discovery of its novel processing enzyme, Icp55. | 2009 Oct 30 |
2 |
| 46 |
19722697 | Iron-sulfur cluster biosynthesis: characterization of a molten globule domain in human NFU. | 2009 Aug 11 |
1 |
| 47 |
18650437 | A novel role for human Nfs1 in the cytoplasm: Nfs1 acts as a sulfur donor for MOCS3, a protein involved in molybdenum cofactor biosynthesis. | 2008 Sep 12 |
5 |
| 48 |
18843040 | Posttranslational regulation of the scaffold for Fe-S cluster biogenesis, Isu. | 2008 Dec |
1 |
| 49 |
17331979 | Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones. | 2007 Apr 15 |
1 |
| 50 |
16341089 | Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. | 2006 Jan 11 |
1 |