Title : Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.

Pub. Date : 2019 May 17

PMID : 31101807






1 Functional Relationships(s)
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Protein Name
Organism
1 The core machinery for de novo biosynthesis of iron-sulfur clusters (ISC), located in the mitochondria matrix, is a five-protein complex containing the cysteine desulfurase NFS1 that is activated by frataxin (FXN), scaffold protein ISCU, accessory protein ISD11, and acyl-carrier protein ACP. Sulfur NFS1 cysteine desulfurase Homo sapiens