Pub. Date : 2013
PMID : 23593335
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The L-cysteine desulfurase NFS1 is localized in the cytosol where it provides the sulfur for molybdenum cofactor biosynthesis in humans. | Sulfur | NFS1 cysteine desulfurase | Homo sapiens |
2 | In humans, the L-cysteine desulfurase NFS1 plays a crucial role in the mitochondrial iron-sulfur cluster biosynthesis and in the thiomodification of mitochondrial and cytosolic tRNAs. | Sulfur | NFS1 cysteine desulfurase | Homo sapiens |
3 | We have previously demonstrated that purified NFS1 is able to transfer sulfur to the C-terminal domain of MOCS3, a cytosolic protein involved in molybdenum cofactor biosynthesis and tRNA thiolation. | Sulfur | NFS1 cysteine desulfurase | Homo sapiens |
4 | Purified NFS1 was used to reconstitute the lacking molybdoenzyme activity of the Neurospora crassa nit-1 mutant, giving additional evidence that NFS1 is the sulfur donor for Moco biosynthesis in eukaryotes in general. | Sulfur | NFS1 cysteine desulfurase | Homo sapiens |
5 | Purified NFS1 was used to reconstitute the lacking molybdoenzyme activity of the Neurospora crassa nit-1 mutant, giving additional evidence that NFS1 is the sulfur donor for Moco biosynthesis in eukaryotes in general. | Sulfur | NFS1 cysteine desulfurase | Homo sapiens |