Lopinavir

ATP binding cassette subfamily B member 1 ; Homo sapiens







21 Article(s)
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1 33063648 Molecular dynamic mechanism(s) of inhibition of bioactive antiviral phytochemical compounds targeting cytochrome P450 3A4 and P-glycoprotein. 2022 Feb 1
2 33032513 Suppression of HIV-1 Viral Replication by Inhibiting Drug Efflux Transporters in Activated Macrophages. 2021 1
3 33759544 Predictive association of ABCB1 C3435T genetic polymorphism with the efficacy or safety of lopinavir and ritonavir in COVID-19 patients. 2021 Apr 2
4 34426410 Successful Prediction of Human Fetal Exposure to P-Glycoprotein Substrate Drugs Using the Proteomics-Informed Relative Expression Factor Approach and PBPK Modeling and Simulation. 2021 Oct 1
5 33312066 Pharmacogenomics landscape of COVID-19 therapy response in Serbian population and comparison with worldwide populations. 2020 Oct 2 1
6 31028820 Solubility and bioavailability enhancement study of lopinavir solid dispersion matrixed with a polymeric surfactant - Soluplus. 2019 Jun 15 1
7 31262902 Co-treatment With HIV Protease Inhibitor Nelfinavir Greatly Increases Late-phase Apoptosis of Drug-resistant KBV20C Cancer Cells Independently of P-Glycoprotein Inhibition. 2019 Jul 1
8 31481446 Anti-HIV and Anti-Hepatitis C Virus Drugs Inhibit P-Glycoprotein Efflux Activity in Caco-2 Cells and Precision-Cut Rat and Human Intestinal Slices. 2019 Nov 2
9 28676669 Carfilzomib resistance due to ABCB1/MDR1 overexpression is overcome by nelfinavir and lopinavir in multiple myeloma. 2018 Feb 6
10 24727459 Amino Acid Prodrugs: An Approach to Improve the Absorption of HIV-1 Protease Inhibitor, Lopinavir. 2014 Apr 10 4
11 23528223 Influence of MDR1 C1236T polymorphism on lopinavir plasma concentration and virological response in HIV-1-infected children. 2013 Jun 10 2
12 20551216 Protease inhibitors atazanavir, lopinavir and ritonavir are potent blockers, but poor substrates, of ABC transporters in a broad panel of ABC transporter-overexpressing cell lines. 2010 Aug 3
13 19207033 ABCB1 polymorphisms and the concentrations of lopinavir and ritonavir in blood, semen and saliva of HIV-infected men under antiretroviral therapy. 2009 Feb 1
14 19960055 Functional role of p-glycoprotein and binding protein effect on the placental transfer of lopinavir/ritonavir in the ex vivo human perfusion model. 2009 3
15 18183034 Effect of an antiretroviral regimen containing ritonavir boosted lopinavir on intestinal and hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected patients. 2008 Jul 2
16 17324111 Multidrug resistance 1 polymorphisms and trough concentrations of atazanavir and lopinavir in patients with HIV. 2007 Mar 1
17 17591027 Synergistic inhibition of protease-inhibitor-resistant HIV type 1 by saquinavir in combination with atazanavir or lopinavir. 2007 2
18 17890284 Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes. 2007 Nov 2
19 12700464 Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoprotein. 2003 May 2 4
20 12902797 The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro. 2003 Aug 15 1
21 14711599 No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment. 2003 Dec 9 2