Cyclosporine

ATP binding cassette subfamily B member 1 ; Homo sapiens







481 Article(s)
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Pub. Year
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1 34935100 In Vitro Evaluation of P-gp-Mediated Drug-Drug Interactions Using the RPTEC/TERT1 Human Renal Cell Model. 2022 Mar 1
2 35629245 Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants. 2022 May 19 1
3 33974505 Association of polymorphism of CYP3A4, ABCB1, ABCC2, ABCG2, NFKB1, POR, and PXR with the concentration of cyclosporin A in allogeneic haematopoietic stem cell transplantation recipients. 2021 Jul 3
4 34269803 Genetic variants associated with cytomegalovirus infection after allogeneic hematopoietic cell transplantation. 2021 Oct 28 1
5 31441337 Clinical Controversy in Transplantation: Tacrolimus Versus Cyclosporine in Statin Drug Interactions. 2020 Feb 1
6 32094096 The role of candidate genetic polymorphisms in the interaction between voriconazole and cyclosporine in patients undergoing allogeneic hematopoietic cell transplantation: An explorative study. 2020 Apr 2
7 32162881 Severe Anaphylaxis During Allogeneic Hematopoietic Stem Cell Transplantation in a Patient with Aplastic Anemia: Case Report of Individualized Pharmaceutical Care and Literature Review. 2020 Mar 1 1
8 32222391 Worsening of Kidney Transplant Function During 2-Year Follow-up Is Associated With the Genetic Variants of CYP3A4, MDR1, and UGT1A9. 2020 Oct 1
9 32682934 Incorporating nonlinear kinetics to improve predictive performance of population pharmacokinetic models for ciclosporin in adult renal transplant recipients: A comparison of modelling strategies. 2020 Oct 1 2
10 30690767 Relationship between allograft cyclosporin concentrations and P-glycoprotein expression in the 1st month following renal transplantation. 2019 May 5
11 30799432 Effect of Multidrug-Resistant 1 (MDR1) and CYP3A4*1B Polymorphisms on Cyclosporine-Based Immunosuppressive Therapy in Renal Transplant Patients. 2019 Feb 25 2
12 30912163 Perpetrator effects of ciclosporin (P-glycoprotein inhibitor) and its combination with fluconazole (CYP3A inhibitor) on the pharmacokinetics of rivaroxaban in healthy volunteers. 2019 Jul 2
13 31090467 Co-encapsulation of docetaxel and cyclosporin A into SNEDDS to promote oral cancer chemotherapy. 2019 Dec 2
14 31156436 A Single Dose of Baicalin Has No Clinically Significant Effect on the Pharmacokinetics of Cyclosporine A in Healthy Chinese Volunteers. 2019 2
15 31261526 Correlation between gene polymorphism and blood concentration of calcineurin inhibitors in renal transplant recipients: An overview of systematic reviews. 2019 Jun 1
16 29222397 Indoxyl Sulfate Upregulates Liver P-Glycoprotein Expression and Activity through Aryl Hydrocarbon Receptor Signaling. 2018 Mar 1
17 29352737 Bronchiolitis obliterans syndrome is associated with increased p-glycoprotein expression and loss of glucocorticoid receptor from steroid-resistant proinflammatory CD8+ T cells. 2018 May 1
18 29568367 The new allosteric inhibitor asciminib is susceptible to resistance mediated by ABCB1 and ABCG2 overexpression in vitro. 2018 Mar 2 1
19 29623717 [Idiopathic thrombocytopenia refractery to therapy of cyclosporine A in clinical practice - case report]. Spring 2018 1
20 30109442 Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules. 2018 Aug 14 1
21 28214069 [Pharmacokinetic drug interaction between miconazole mucoadhesive tablet and tacrolimus: About 3 case-reports in transplant patients]. 2017 Sep 1
22 28623111 Reversal of ABCB1 mediated efflux by imatinib and nilotinib in cells expressing various transporter levels. 2017 Aug 1 1
23 28736004 Lack of Association Between TGF-β1 and MDR1 Genetic Polymorphisms and Cyclosporine-Induced Gingival Overgrowth in Kidney Transplant Recipients: A Meta-analysis. 2017 Jul - Aug 1
24 28739698 Highly Eribulin-resistant KBV20C Oral Cancer Cells Can Be Sensitized by Co-treatment with the Third-generation P-Glycoprotein Inhibitor, Elacridar, at a Low Dose. 2017 Aug 1
25 28739760 Cyclosporin A Reversed Chemoresistance of a Patient with Pure Red Cell Aplasia Secondary to Thymoma. 2017 Aug 1
26 28952408 Influence of CYP3A and ABCB1 polymorphisms on cyclosporine concentrations in renal transplant recipients. 2017 Nov 2
27 29381954 Effect of MDR1 C1236T polymorphism on cyclosporine pharmacokinetics: A systematic review and meta-analysis. 2017 Nov 4
28 26353895 Drug-Drug Interactions with the NS3/4A Protease Inhibitor Simeprevir. 2016 Feb 1
29 26563728 (11)C- and (18)F-Labeled Radioligands for P-Glycoprotein Imaging by Positron Emission Tomography. 2016 Jan 5 1
30 26585254 Clinical Applications of Simultaneous PET/MR Imaging Using (R)-[11C]-Verapamil with Cyclosporin A: Preliminary Results on a Surrogate Marker of Drug-Resistant Epilepsy. 2016 Apr 1
31 26912097 Clinical determinants of calcineurin inhibitor disposition: a mechanistic review. 2016 2
32 27016408 Plasma protein binding limits the blood brain barrier permeation of the pyrethroid insecticide, deltamethrin. 2016 May 27 4
33 27283486 Imaging the impact of cyclosporin A and dipyridamole on P-glycoprotein (ABCB1) function at the blood-brain barrier: A [(11)C]-N-desmethyl-loperamide PET study in nonhuman primates. 2016 Aug 25 4
34 27374283 Changes in ABCB1 mRNA Expression in Peripheral Blood Cells before and after Renal Transplantation. 2016 2
35 27836711 Effect of cigarette smoke extract on P-glycoprotein function in primary cultured and newly developed alveolar epithelial cells. 2016 Dec 1
36 28164520 The Effect of ABCB1 Polymorphisms on Serial Tacrolimus Concentrations in Stable Austrian Long-Term Kidney Transplant Recipients. 2016 Oct 1 1
37 25240575 Impact of CYP3A4 and MDR1 gene (G2677T) polymorphisms on dose requirement of the cyclosporine in renal transplant Egyptian recipients. 2015 Jan 7
38 25407255 Effects of rifampin, cyclosporine A, and probenecid on the pharmacokinetic profile of canagliflozin, a sodium glucose co-transporter 2 inhibitor, in healthy participants. 2015 Feb 1
39 25536375 The Effect of ABCB1 C3435T Polymorphism on Cyclosporine Dose Requirements in Kidney Transplant Recipients: A Meta-Analysis. 2015 Aug 9
40 25673014 The donor ABCB1 (MDR-1) C3435T polymorphism is a determinant of the graft glomerular filtration rate among tacrolimus treated kidney transplanted patients. 2015 May 1
41 25857708 2'[(18)F]-fluoroethylrhodamine B is a promising radiotracer to measure P-glycoprotein function. 2015 Jul 10 2
42 25891084 Diltiazem augments the influence of MDR1 genotype status on cyclosporine concentration in Chinese patients with renal transplantation. 2015 Jul 5
43 26004871 Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells. 2015 Aug 1 1
44 26107754 Association of SNPs with the efficacy and safety of immunosuppressant therapy after heart transplantation. 2015 1
45 26153782 P-glycoprotein is expressed and causes resistance to chemotherapy in EBV-positive T-cell lymphoproliferative diseases. 2015 Oct 3
46 26618109 Disease control by regulation of P-glycoprotein on lymphocytes in patients with rheumatoid arthritis. 2015 Nov 20 1
47 27022464 Chronic P-glycoprotein inhibition increases the brain concentration of escitalopram: potential implications for treating depression. 2015 Dec 2
48 24212378 In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold. 2014 Feb 2
49 24219005 Phase II and pharmacological study of oral docetaxel plus cyclosporin A in anthracycline pre-treated metastatic breast cancer. 2014 May 3
50 24364805 Predicting the outer boundaries of P-glycoprotein (P-gp)-based drug interactions at the human blood-brain barrier based on rat studies. 2014 Feb 3 4