Title : Drug-Drug Interactions with the NS3/4A Protease Inhibitor Simeprevir.

Pub. Date : 2016 Feb

PMID : 26353895






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Cyclosporine is an inhibitor of OATP1B1/3, BCRP and P-gp, and a mild inhibitor of CYP3A; cyclosporine causes a significant increase in simeprevir plasma concentrations, and coadministration is not recommended. Cyclosporine ATP binding cassette subfamily B member 1 Homo sapiens