Vinca Alkaloids

ATP binding cassette subfamily B member 1 ; Homo sapiens







57 Article(s)
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1 34126072 CMP25, a synthetic new agent, targets multidrug resistance-associated protein 7 (MRP7/ABCC10). 2021 Aug 1
2 29145976 Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins. 2017 May 3
3 27725879 Targeting ABCB1-mediated tumor multidrug resistance by CRISPR/Cas9-based genome editing. 2016 2
4 25283245 Differential involvement of glutathione S-transferase mu 1 and multidrug resistance protein 1 in melanoma acquired resistance to vinca alkaloids. 2015 Feb 2
5 25685543 P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review. 2015 Jan 1
6 21374643 Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression. 2012 Nov 2
7 21680190 2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance. 2011 Jul 15 4
8 19442049 Multidrug resistance through the spectacle of P-glycoprotein. 2009 May 3
9 19470292 Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy. 2009 1
10 17620438 Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein. 2007 Jul 4
11 18528466 The individualization of cancer therapy: the unexpected role of p53. 2006 2
12 15457126 Ex vivo reversal of chemoresistance by tariquidar (XR9576). 2004 Oct 2
13 20641303 99mTc-2-Methoxyisobutylisonitrile 2004 1
14 20641310 [N-methyl-11C]4-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-2,2-diphenyl-N-methyl-butanamide 2004 1
15 20641391 1-(9H-Carbazol-4-yloxy)-3-(2-(2-[11C]methoxyphenoxy)ethylamino)-propan-2-ol 2004 3
16 20641759 2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-[11C]methyl-amino]-2-propan-2-yl-pentanenitrile 2004 3
17 20862794 6,7-Dimethoxy-2-[3-(5-[11C]methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-1,2,3,4-tetrahydro-isoquinoline 2004 1
18 20862795 6,7-Dimethoxy-2-{3-[4-[11C]methoxy-3,4-dihydro-2H-naphthalen-(1E)-ylidene]-propyl}-1,2,3,4-tetrahydro-isoquinoline 2004 1
19 12490309 Modulation of vinca-alkaloid induced P-glycoprotein expression by indole-3-carbinol. 2003 Jan 28 1
20 11850258 Doxycycline induces expression of P glycoprotein in MCF-7 breast carcinoma cells. 2002 Mar 1
21 12203099 Phase I and pharmacokinetic study of vinblastine and high-dose megestrol acetate. 2002 Sep 3
22 12516967 Identification and characterization of the canine multidrug resistance-associated protein. 2002 Dec 2
23 11552980 Cross-resistance to cytosine arabinoside in a multidrug-resistant human promyelocytic cell line selected for resistance to doxorubicin: implications for combination chemotherapy. 2001 Sep 3
24 10739113 The prognostic significance of membrane transport-associated multidrug resistance (MDR) proteins in leukemia. 2000 Mar 2
25 11062698 The human multidrug resistance gene (MDR-1): immunocytochemical detection of its expression in oral SCC. 2000 Sep-Oct 1
26 11187897 Phase I study of cinchonine, a multidrug resistance reversing agent, combined with the CHVP regimen in relapsed and refractory lymphoproliferative syndromes. 2000 Dec 2
27 10092063 MDR1 gene expression in primary and advanced breast cancer. 1999 Mar 2
28 9687882 The multidrug resistance in human leukemias. Minireview. 1998 1
29 9744556 Kinetic analysis in living cells of the inhibition of the P-glycoprotein-mediated efflux of anthracyclines by vinca alkaloids. 1998 Jul 3 3
30 9780138 Therapeutic approach to drug resistant tumors. 1998 Oct 1
31 9864280 Modulation of the tumor disposition of vinca alkaloids by PSC 833 in vitro and in vivo. 1998 Dec 1
32 10021886 [The causes of treatment ineffectiveness in acute myelogenous leukemia--the role of blast resistance to cytotoxic drugs]. 1998 1
33 8546904 Modulation of vinblastine cytotoxicity by dilantin (phenytoin) or the protein phosphatase inhibitor okadaic acid involves the potentiation of anti-mitotic effects and induction of apoptosis in human tumour cells. 1996 Jan 2
34 8599869 Cross-resistance and collateral sensitivity to natural product drugs in cisplatin-sensitive and -resistant rat lymphoma and human ovarian carcinoma cells. 1996 1
35 8704189 Correlation of P-glycoprotein expression and function in childhood acute leukemia: a children's cancer group study. 1996 Jul 1 2
36 9816243 Retroviral transfer and expression of the human multiple drug resistance (MDR) gene in peripheral blood progenitor cells. 1996 May 1
37 7540457 Expression of MDR1 by normal bone marrow cells and its implication for leukemic hematopoiesis. 1995 Feb 1
38 7598747 Allosteric regulation of [3H]vinblastine binding to P-glycoprotein of MCF-7 ADR cells by dexniguldipine. 1995 Jun 16 1
39 7734315 Rapid up-regulation of mdr1 expression by anthracyclines in a classical multidrug-resistant cell line. 1995 May 1
40 8669809 Immunocytochemical observation of multidrug resistance (MDR) p170 glycoprotein expression in human osteosarcoma cells. The clinical significance of MDR protein overexpression. 1995 Nov-Dec 1
41 7807193 Drug resistance in brain tumors. 1994 1
42 7909572 Clinical relevance of P-glycoprotein expression in haematological malignancies. 1994 Apr 1
43 7912754 Multidrug resistance phenotype in patients with chronic lymphocytic leukemia as detected by immunofluorescence (FACS) and northern blot analysis. 1994 Jul 2
44 7915508 In vivo expression of P-glycoprotein in a human colon carcinoma xenograft is modulated by therapy with free and monoclonal antibody-conjugated vinca alkaloids. 1994 May-Jun 1
45 7681059 Human P-glycoprotein transports cyclosporin A and FK506. 1993 Mar 25 1
46 7765326 Multidrug resistance (MDR) genes in haematological malignancies. 1993 1
47 7765329 Differing patterns of cross-resistance resulting from exposures to specific antitumour drugs or to radiation in vitro. 1993 1
48 8094716 The development and characterization of Vinca alkaloid-resistant Caco-2 human colorectal cell lines expressing mdr-1. 1993 Feb 20 1
49 1334113 Pharmacologic validation of human tumor clonogenic assays based on pleiotropic drug resistance: implications for individualized chemotherapy and new drug screening programs. 1992 Nov 1
50 1348013 Reversal of Vinca alkaloid resistance by anti-P-glycoprotein monoclonal antibody HYB-241 in a human tumor xenograft. 1992 Apr 1 1