Title : Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression.

Pub. Date : 2012 Nov

PMID : 21374643






2 Functional Relationships(s)
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1 Cellular overproduction of P-glycoprotein (P-gp), which acts as an efflux pump for various anticancer drugs (e.g. anthracyclines, Vinca alkaloids, taxanes, epipodophyllotoxins, and some of the newer antitumor drugs) is one of the more relevant mechanisms underlying MDR. Vinca Alkaloids ATP binding cassette subfamily B member 1 Homo sapiens
2 Cellular overproduction of P-glycoprotein (P-gp), which acts as an efflux pump for various anticancer drugs (e.g. anthracyclines, Vinca alkaloids, taxanes, epipodophyllotoxins, and some of the newer antitumor drugs) is one of the more relevant mechanisms underlying MDR. Vinca Alkaloids ATP binding cassette subfamily B member 1 Homo sapiens